Biomedical sciences publications

Here, we tested the hypothesis that wild-type Wistar rats, exposed to vaporized alcohol ensuring higher BALs than typically achieved with voluntary consumption in rodents, would model MRI findings in the…

Stress-induced analgesia (SIA) is a key component of the defensive behavioral “fight-or-flight” response. Although the neural substrates of SIA are incompletely understood, previous studies have implicated the hypocretin/orexin (Hcrt) and…

In this study we use hydrodynamic calculations to explore possible impact conditions and sample locations on the L6 parent body for the highly shocked L6 chondrite RC106.

This study aimed to determine the rates of quitline re-enrollment and to compare the responses of people of varying racial/ethnic identities to invitations utilizing different communication strategies.

L-selectin has been suggested to play a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Here we demonstrate that L-selectin–/– SJL mice are susceptible…

Neuropathological studies of chronic alcoholism indicate that loss of neurons is selective to frontal cortex (Courville, 1955, Harper and Kril, 1990) with little evidence for widespread cell loss (Harper, 1998,…

We introduce a method for systematically prioritizing single nucleotide polymorphisms (SNPs) for further study after a GWAS. The method combines evidence across multiple domains including statistical evidence of genotype–phenotype correlation,…

Components of the corticocerebellar circuit and the midbrain individually play a central role in addictive processes and have been associated with altered volumes and impairment of cognitive flexibility in alcohol-dependent…

In the present study, we tested the hypothesis that abrupt discontinuation of methamphetamine would also cause withdrawal-like behavior in planarians and that the withdrawal-like behavior would be prevented by nociceptin,…

We found evidence for association between four SNPs in GABRA4, two SNPs in GABRA2 and one SNP in GABRE with nicotine dependence.

In cases where surgical reconstruction is not an option, placement of osseo-integrated implants for an auricular prosthesis can be done in 1 or 2 stages in a relatively short period…